Polymyxin B FDA Link Generic

A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.

Also Known As:

Aerosporin; Polymyxin B Sulfate

Pharmalogical Action Categories:

Anti-Bacterial Agents

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Polymyxins: 729
      - Polymyxin B: 1374
Lipids: 114793
- Lipopeptides: 626
  - Polymyxins: 729
    - Polymyxin B: 1374
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Antimicrobial Cationic Peptides: 414
        Polymyxins: 729
        Polymyxin B: 1374
- Peptides: 82426
  - Antimicrobial Peptides: 3727
    - Antimicrobial Cationic Peptides: 414
      - Polymyxins: 729
        Polymyxin B: 1374
  - Cyclic Peptides: 530
    - Polymyxins: 729
      - Polymyxin B: 1374
  - Antimicrobial Cationic Peptides: 414
    - Polymyxins: 729
      - Polymyxin B: 1374

Michael Voget Selected Research

Michael Voget Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure